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Abstract

Xanthogranulomatous cholecystitis (XGC) is an uncommon form of chronic cholecystitis[1] characterized by inflammation and infiltration of gall bladder (GB) wall by lymphocytes and multinucleated histiocytic giant cells. There is transudation of bile into gall bladder wall and involvement of the Rokitansky-Aschoff sinuses leading to formation of submucosal abscess and xanthogranulomas.[2] On CECT, they appear as submucosal hypoattenuating nodules and circumferential wall thickening of gallbladder wall, a sign highly specific of XGC.[3]

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How to Cite
Amit Shrivastava, Irbinder Kour Bali, Srishti Mann, & Gunjan Jindal. (2024). Xanthogranulomatous Cholecystitis - An Intimidating Diagnostic Dilemma - A Case Report. Journal of Evolution of Medical and Dental Sciences, 13(1), 27–29. https://doi.org/10.14260/jemds.v13i1.544

References

  1. Makino I, Yamaguchi T, Sato N, et al. Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma with a false-positive result on fluorodeoxyglucose PET. World J Gastroenterol 2009;15(29):3691-3.
  2. Rammohan A, Cherukuri SD, Sathyanesan J, et al. Xanthogranulomatous cholecystitis masquerading as gallbladder cancer: can it be diagnosed preoperatively? Gastroenterol Res Pract 2014;2014:253645.
  3. Reghunath A, Kushvaha S, Ghasi RG, et al. Chronic gallbladder wall thickening: Is it always malignancy? SA J Radiol 2020;24(1):1844.
  4. McCoy JJ, Vila R, Petrossian G, et al. Xanthogranulomatous cholecystitis. Report of two cases. J S C Med Assoc 1976;72(3):78-9.
  5. Houston JP, Collins MC, Cameron I, et al. Xanthogranulomatous cholecystitis. Br J Surg 1994;81(7):1030-2.
  6. Zhao F, Lu PX, Yan SX, et al. CT and MR features of xanthogranulomatous cholecystitis: an analysis of consecutive 49 cases. Eur J Radiol 2013;82(9):1391-7.
  7. Goshima S, Chang S, Wang JH, et al. Xanthogranulomatous cholecystitis: diagnostic performance of CT to differentiate from gallbladder cancer. Eur J Radiol 2010;74(3):e79-83.
  8. Suzuki H, Wada S, Araki K, et al. Xanthogranulomatous cholecystitis: difficulty in differentiating from gallbladder cancer. World J Gastroenterol 2015;21(35):10166-73.
  9. Ladefoged C, Lorentzen M. Xanthogranulomatous cholecystitis. A clinicopathological study of 20 cases and review of the literature. APMIS 1993;101(11):869-75.