Main Article Content
Abstract
BACKGROUND
The word “dengue” originates from the Bantu phrase Ka- dinga pepo, meaning “cramp-like seizure”. Breakbone fever viruses are enclosed in the family Flaviviridae and the virus has four serotypes through-about to as Dengue virus-1, DV-2, DV-3, and DV-4. Breakbone fever virus is a ribonucleic acid virus, encapsulated and is positive-stranded and consists of 3 structural macromolecule genes that encrypt the nucleocapsid or core (c) macromolecule, a membrane-associated (M) macromolecule, an engulfed (E) conjugated protein and 7 non-structural (NS) proteins. Dengue virus is principally transmitted by the dipteron / Aedes aegypti mosquito, two-winged insects and conjointly by the Asian tiger mosquito. The purpose of this study was to find an association of gall bladder wall thickening and haematocrit values with severity in patients with dengue fever admitted to Mahatma Gandhi Medical College & Hospital, Sitapura, Jaipur (a tertiary care unit).
METHODS
It was a hospital-based observational study, conducted on all patients who were positive for dengue NS1 Antigen and IgM serology & who visited the Department of General Medicine in Mahatma Gandhi Medical College & Hospital, Sitapura, Jaipur from January 2020 to June 2021 were included in the study. All data were collected and analyzed by EPI-info software.
RESULTS
The association between gall bladder thickness and PCV was found statistically significant. Associations between PCV and prognosis and that of gall bladder thickness and prognosis were also found statistically significant.
CONCLUSIONS
We concluded that gall bladder wall thickness and haematocrit values are significant contributors to the assessment of the severity of dengue fever. The main advantage of this method is that it is a fast and easily approachable method and can be easily practised in most centres.
Keywords
Article Details
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References
- Tripathi P, Kumar R, Tripathi S, et al. Descriptive epidemiology of dengue transmission in Utta Pradesh. Indian Pediatr 2008;45(4):315-8.
- Wahala WM, de Silva AM. The human antibody response to dengue virus infection. Vireuses 2011;3(12):2374-95.
- Bhatt S, Gething PW, Brady OJ, et al. The global distribution and burden of dengue. Nature 2013;496(7446):504-7.
- Thomas SJ, Endy TP. Critical issues in dengue vaccine development. Curr Opin Infect Dis 2011;24(5):442-50.
- Chaturvedi U, Nagar R. Dengue and dengue haemorrhagic fever. J Biosci 2008;33(4):429-41.
- Deshwal R, Qureshi MI, Singh R. Clinical and laboratory profile of dengue fever. J Assoc Physicians India 2015;63(12):30-2.
- Chajhlana SPS, Mahabhasyam RN, Varaprasada MSM, et al. Socio demographic and clinical profile of dengue fever cases at a tertiary care hospital, Hyderabad, Telangana. Int J Community Med Public Health 2017;4(6):2027-30.
- Jahnavi K, Srinivasulu T. Study of incidence, manifestations and complications of dengue fever. Int J Adv Med 2018;5(1):137-40.
- Santosh VR, Patil PG, Srinath MG, et al. Sonography in the diagnosis and assessment of dengue fever. J Clin Imaging Sci 2014;4:14.
- Patil ST, Virupaksha KL, Kavyashree NG. A study of clinical manifestations and complications of dengue fever in medical college hospital. Int J Med Res Rev 2019;7(3):224-30.
References
Tripathi P, Kumar R, Tripathi S, et al. Descriptive epidemiology of dengue transmission in Utta Pradesh. Indian Pediatr 2008;45(4):315-8.
Wahala WM, de Silva AM. The human antibody response to dengue virus infection. Vireuses 2011;3(12):2374-95.
Bhatt S, Gething PW, Brady OJ, et al. The global distribution and burden of dengue. Nature 2013;496(7446):504-7.
Thomas SJ, Endy TP. Critical issues in dengue vaccine development. Curr Opin Infect Dis 2011;24(5):442-50.
Chaturvedi U, Nagar R. Dengue and dengue haemorrhagic fever. J Biosci 2008;33(4):429-41.
Deshwal R, Qureshi MI, Singh R. Clinical and laboratory profile of dengue fever. J Assoc Physicians India 2015;63(12):30-2.
Chajhlana SPS, Mahabhasyam RN, Varaprasada MSM, et al. Socio demographic and clinical profile of dengue fever cases at a tertiary care hospital, Hyderabad, Telangana. Int J Community Med Public Health 2017;4(6):2027-30.
Jahnavi K, Srinivasulu T. Study of incidence, manifestations and complications of dengue fever. Int J Adv Med 2018;5(1):137-40.
Santosh VR, Patil PG, Srinath MG, et al. Sonography in the diagnosis and assessment of dengue fever. J Clin Imaging Sci 2014;4:14.
Patil ST, Virupaksha KL, Kavyashree NG. A study of clinical manifestations and complications of dengue fever in medical college hospital. Int J Med Res Rev 2019;7(3):224-30.